Detect Bladder Cancer Early – At home urine test

  • Revolutionary new genetic test for anyone diagnosed with blood in the urine
  • A negative result removes the need for a cystoscopy
  • Detects a new bladder cancer early, identifies relapse, and monitors minimal residual disease
  • High sensitivity, equivalent to cystoscopy
  • 23 genes tested for mutations found in bladder cancers
  • Non-invasive pain-free urine test at home
  • Test approved and reimbursed by Bupa UK health insurance*
  • Testing, analysis and interpretation performed in UKAS accredited ISO15189 Genomics Laboratory
  • Report interpreted by HCPC registered Clinical Scientists
  • Results within 10-15 working days

      *Eligibility criteria apply.


Innovative new genetic test for the early detection of bladder cancer

It’s an unfortunate fact that 1 in 2 people in the UK will be diagnosed with cancer in their lifetime. However, it is well-known that usually the earlier the diagnosis, the better the outcome. Therefore, as well as searching for new treatments, cancer research has focused on finding new ways to detect cancer quickly and easily at the earliest stage possible to improve survival rates.

Currently, people with blood in the urine (haematuria) and suspected of having bladder cancer are referred for a cystoscopy - an uncomfortable hospital procedure that involves a camera being passed through the urethra into the bladder. A genetic test for identifying all stages of bladder cancer from a simple urine sample is an effective, non-invasive method with equivalent sensitivity and specificity to a cystoscopy.

This 'liquid biopsy' technology sequences DNA in the urine to identify mutations in 23 different genes which are found in 96% of all bladder cancers. The ease of providing a urine sample in the comfort of your own home over a cystoscopy procedure in hospital is clearly advantageous. Not only does this make it highly accessible for those experiencing haematuria with an unknown cause, but as bladder cancer has one of the highest reoccurrence rates of any cancer, it is also beneficial for relapse surveillance.

This pioneering non-invasive accurate genetic test for bladder cancer from a home urine sample has 85% specificity and up to 90% sensitivity and now available to BUPA bladder cancer policy holders.

Why this GALEAS™ Bladder Cancer Test?

Have you been diagnosed with blood in the urine (haematuria) and awaiting a cystoscopy to rule out cancer as the cause? The GALEAS™ Bladder Cancer Test is a molecular biomarker test that can detect genetic mutations associated with 96% of bladder cancers at all stages and grades, with equivalent results to cystoscopy. It provides a much more convenient way of sampling which can also exclude the diagnosis altogether, and removes the need for your cystoscopy!

Whilst other urine tests for bladder cancer are available, they are often based on the levels of proteins or RNA in the urine. These are not specific, nor causally linked, to bladder cancer and therefore lack the specificity and sensitivity to detect small or low-grade tumours. Unlike other tests, this GALEAS™ Bladder Cancer Test also covers a wider range of DNA markers, so it is less likely to miss a cancer.

Early diagnosis of the disease is crucial with more than 80% of people diagnosed at the earliest stage surviving at least five years compared to less than 10% diagnosed at the latest stage.


This non-invasive pain-free urine test is simple, easy, and can be done at home with no appointment needed. After sending away your sample, the laboratory will analyse your urine and generate a clear and understandable report of the findings. This is then emailed directly to you, and the results can be discussed further with your doctor if needed. It is also able to streamline diagnosis of different types of bladder cancer, non-muscle-invasive bladder cancer (NMIBC) and muscle-invasive bladder cancer (MIBC).

Watch how our test works
A complete sample to report solution for your bladder cancer concerns from the comfort of your home environment

The GALEAS™ Bladder Cancer Test analyses the DNA in your urine for the presence of mutations associated with all types of bladder cancer and results are shared directly with you.

1. Order your kit

Order online and we will send you a urine sampling kit containing everything you need.

2. Take the sample

Collect your urine sample at home then return the sample in the pre-paid Tracked 48 packaging.

3. Sample is processed in an ISO15189 Accredited Lab

DNA is extracted from your urine sample, sequenced, analysed and reported back to you within 14 working days.

4. Results sent to you

Results are sent via email directly to you. If a mutation associated with bladder cancer is detected you will be advised to contact your doctor immediately.

What's included in your GALEAS™ Bladder Cancer Test kit:

Your kit will include easy to follow instructions for use plus the following items:

A) Urine sample collection tube (50ml required)
B) Protective transport mailer for urine tube
C) Pack Contents/Instructions For Use card
D) Galeas Bladder Cancer Test Consent Form
E) Tamperproof sticker
F) Pre-paid postage return box

HPV Kit Contents
What will your report tell you?

There are two possible outcomes:

Bladder cancer variants not detected (~90% of cases);
No evidence of cancer-associated somatic genomic variants detected suggesting the presence of bladder cancer is unlikely.

Bladder cancer variants detected (~10% of cases);
Evidence of cancer-associated somatic genomic variants detected suggesting there is high likelihood that cancer is present. Appropriate clinical recommendations will be made. You will be advised that it is essential to follow up with your doctor immediately as currently the definitive diagnosis of bladder cancer is confirmed with a cystoscopy.

Covered by Bupa Private Health Insurance?
Reaffirming the clinical value of this test, Bupa has become the first health insurer in the UK to reimburse the cost of the GALEAS™ Bladder Cancer Test for its policy holders. Eligibility criteria apply, please visit the Bupa website or contact Bupa directly for more information.
Learn more about the genetics of cancer and the genes included:

What is cancer?

Cancer is uncontrolled cell growth in an area of the body. When uncontrolled cell growth happens, it can form a tumour. Cancerous tumours can spread to other tissues which can affect how the body functions. Cancer is caused by variants in genes which normally control the growth and replication of cells. For more information please see Cancer Research UK.

What is bladder cancer?

A type of cancer causing growth of abnormal tissue in the bladder lining. In some cases, the tumour can spread into the bladder muscle. The most common symptom of bladder cancer is haematuria (blood in the urine), which is usually painless.

Can I get tested if I have cancer?

Yes. The test is available to all adults over the age of 18 experiencing blood in the urine. Any known health conditions or family history of cancer will not impact the results. Besides being an incredibly useful tool for diagnosing a first case of bladder cancer, this test is also useful for people in remission from bladder cancer for surveillance monitoring to assess whether the cancer has returned. However if you already know you currently have bladder cancer, this test will not provide any further information of clinical significance.

What do I do if DNA mutations are found?

Whilst this test is extremely sensitive and specific, currently the only way to confirm a bladder cancer diagnosis is through a cystoscopy in hospital. If your report shows a positive result, you must contact your doctor immediately so that you can be referred for a cystoscopy.

Does a negative result mean I don’t have cancer?

A negative result means it is almost certain you do not have bladder cancer. However blood in the urine is a symptom that should not be ignored and it is recommended that you still speak to your doctor to determine the cause.

What is Next Generation Sequencing?

Next Generation Sequencing (NGS) is a large-scale, high-throughput technology that allows the order of nucleotide bases within a genome to be studied. NGS alongside bioinformatic analysis is widely used in both the medical healthcare industry as well as within clinical research to investigate different health conditions, including cancer.

How are my results analysed and interpreted?

The team of HCPC registered clinical scientists at Informed Genomics will interpret your test results in accordance to well recognised best practice guidelines.

What will happen to my results?

Your results will be interpreted by our team of expert clinical scientists and the results will be returned securely to you by email. All results are treated as fully confidential, and we will not share any personal details or test results with any third parties without your consent. Should you share your result with your GP or other healthcare provider, our result may become part of your record with them.

What will happen to my sample after testing?

After completion of the testing process, the sample will be stored. Please refer to the consent information for further information regarding storage of samples and data.

What happens if my urine collection device breaks or I need a replacement?

Please contact the laboratory via to request another collection device, or for any further questions regarding this test.

What does a positive result mean?

Detection of mutated DNA in your urine sample means that there are faulty cells in your bladder and indicates that bladder cancer is highly likely to be the cause of your haematuria. It is therefore extremely important that this result is followed up with your doctor.

Will the cost of this test be covered by my private health insurance?

The GALEAS™ Bladder Cancer Test has been approved by Bupa UK and so you may be eligible to claim back the cost of this test through your private medical insurance. Eligibility criteria apply, please contact Bupa for more information on whether you will be covered for this test.